While all Valencian mob damage (mainly in the southern part of the desert) seems higher then it should be, these cases are not particularly unmanageable(though the mob density in crescents means a lagspike is a life or death coin toss) though i have noticed many mobs tend to hit you while quite far away despite being a melee mob (http://bddatabase.net/us/theme/4852/ seems to be a consistent example of this behavior)

The main issue i would like to point out is the Elite mobs and Bosses
my current Class is Dark Knight and my current DP is 228 with + 20 to DR from full ultimate grunils and 2 +5 DR gems and another +5 all DR from food (also when dark knights use their block skill they get another +12 DP)
the extreme examples i have encountered are
http://bddatabase.net/us/npc/27086/ Defense Ordnance (part of the quest http://bddatabase.net/us/quest/5529/5/ Grave of a King)
http://bddatabase.net/us/npc/21265/ Crescent Chief Gatekeeper
http://bddatabase.net/us/npc/27065/ Magram
http://bddatabase.net/us/npc/27064/ Khalk
http://bddatabase.net/us/npc/23736/ Ancient Puturum

these mobs with my current DP/DR hit for anywhere between 2.5k to 5k a hit, i have even seen Puturum hit for 10k